7F50
X-ray crystal structure of Y149A mutated Hsp72-NBD in complex with AMPPnP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock 70 kDa protein 1B | polymer | 386 | 42673.2 | 1 | UniProt (P0DMV9) Pfam (PF00012) | Homo sapiens (Human) | Heat shock 70 kDa protein 2,HSP70-2,HSP70.2 |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | E (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | F (A) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence modifications
A: 3 - 380 (UniProt: P0DMV9)
| PDB | External Database | Details |
|---|---|---|
| Ala 149 | Tyr 149 | engineered mutation |
| Leu 381 | - | expression tag |
| Glu 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42673.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 590.3 | |
| All* | Total formula weight | 43263.4 |
