7F4U
Cryo-EM structure of TELO2-TTI1-TTI2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Telomere length regulation protein TEL2 homolog | polymer | 837 | 91846.9 | 1 | UniProt (Q9Y4R8) Pfam (PF10193) | Homo sapiens (human) | Protein clk-2 homolog,hCLK2 |
| 2 | B (B) | TELO2-interacting protein 1 homolog | polymer | 1095 | 117124.6 | 1 | UniProt (O43156) Pfam (PF21547) | Homo sapiens (human) | Protein SMG10 |
| 3 | C (C) | TELO2-interacting protein 2 | polymer | 508 | 54944.1 | 1 | Homo sapiens (human) |
Sequence modifications
B: 1 - 1089 (UniProt: O43156)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Unk 166 | Lys 166 | conflict |
| Unk 167 | Ser 167 | conflict |
| Unk 168 | Lys 168 | conflict |
| Unk 169 | Gln 169 | conflict |
| Unk 170 | Ile 170 | conflict |
| Unk 171 | Lys 171 | conflict |
| Unk 172 | Ile 172 | conflict |
| Unk 173 | Ala 173 | conflict |
| Unk 174 | Ala 174 | conflict |
| Unk 175 | Leu 175 | conflict |
| Unk 176 | Lys 176 | conflict |
| Unk 177 | Cys 177 | conflict |
| Unk 178 | Leu 178 | conflict |
| Unk 179 | Gln 179 | conflict |
| Unk 180 | Val 180 | conflict |
| Unk 181 | Leu 181 | conflict |
| Unk 182 | Leu 182 | conflict |
| Unk 183 | Leu 183 | conflict |
| Unk 184 | Gln 184 | conflict |
| Unk 185 | Cys 185 | conflict |
| Unk 193 | Ser 193 | conflict |
| Unk 194 | Leu 194 | conflict |
| Unk 195 | Asp 195 | conflict |
| Unk 196 | Glu 196 | conflict |
| Unk 197 | Leu 197 | conflict |
| Unk 198 | Glu 198 | conflict |
| Unk 199 | Gln 199 | conflict |
| Unk 200 | Lys 200 | conflict |
| Unk 201 | Gln 201 | conflict |
| Unk 202 | Leu 202 | conflict |
| Unk 203 | Gly 203 | conflict |
| Unk 204 | Asp 204 | conflict |
| Unk 205 | Leu 205 | conflict |
| Unk 206 | Phe 206 | conflict |
| Unk 207 | Ala 207 | conflict |
| Unk 208 | Ser 208 | conflict |
| Unk 209 | Phe 209 | conflict |
| Unk 210 | Leu 210 | conflict |
| Unk 211 | Pro 211 | conflict |
| Unk 212 | Gly 212 | conflict |
| Unk 213 | Ile 213 | conflict |
| Unk 214 | Ser 214 | conflict |
| Unk 215 | Thr 215 | conflict |
| Unk 216 | Ala 216 | conflict |
| Unk 217 | Leu 217 | conflict |
| Unk 218 | Thr 218 | conflict |
| Unk 219 | Arg 219 | conflict |
| Unk 220 | Leu 220 | conflict |
| Unk 221 | Ile 221 | conflict |
| Unk 222 | Thr 222 | conflict |
| Unk 857 | Pro 857 | conflict |
| Unk 858 | Leu 858 | conflict |
| Unk 859 | Gln 859 | conflict |
| Unk 860 | Ile 860 | conflict |
| Unk 861 | Gln 861 | conflict |
| Unk 862 | Ile 862 | conflict |
| Unk 863 | Ala 863 | conflict |
| Unk 864 | Met 864 | conflict |
| Unk 865 | Asp 865 | conflict |
| Unk 866 | Val 866 | conflict |
| Unk 867 | Met 867 | conflict |
| Unk 868 | Glu 868 | conflict |
| Unk 869 | Arg 869 | conflict |
| Unk 870 | Cys 870 | conflict |
| Unk 871 | Ile 871 | conflict |
| Unk 872 | His 872 | conflict |
| Unk 873 | Leu 873 | conflict |
| Unk 874 | Leu 874 | conflict |
| Unk 875 | Ser 875 | conflict |
| Unk 876 | Asp 876 | conflict |
| Unk 877 | Lys 877 | conflict |
| Unk 878 | Asn 878 | conflict |
| Unk 879 | Leu 879 | conflict |
| Unk 880 | Gln 880 | conflict |
| Unk 881 | Ile 881 | conflict |
| Unk 882 | Arg 882 | conflict |
| Unk 883 | Leu 883 | conflict |
| Unk 884 | Lys 884 | conflict |
| Unk 885 | Val 885 | conflict |
| Unk 886 | Leu 886 | conflict |
| Unk 887 | Asp 887 | conflict |
| Unk 888 | Val 888 | conflict |
| Unk 889 | Leu 889 | conflict |
| Unk 890 | Asp 890 | conflict |
| Unk 891 | Leu 891 | conflict |
| Unk 892 | Cys 892 | conflict |
| Unk 893 | Val 893 | conflict |
| Unk 894 | Val 894 | conflict |
| Unk 895 | Val 895 | conflict |
| Unk 896 | Leu 896 | conflict |
| Unk 897 | Gln 897 | conflict |
| Unk 898 | Ser 898 | conflict |
| Unk 899 | His 899 | conflict |
| Unk 900 | Lys 900 | conflict |
| Unk 901 | Asn 901 | conflict |
| Unk 902 | Gln 902 | conflict |
| Unk 903 | Leu 903 | conflict |
| Unk 904 | Leu 904 | conflict |
| Unk 905 | Pro 905 | conflict |
| Unk 906 | Leu 906 | conflict |
| Unk 907 | Ala 907 | conflict |
| Unk 908 | His 908 | conflict |
| Unk 909 | Gln 909 | conflict |
| Unk 910 | Ala 910 | conflict |
| Unk 911 | Trp 911 | conflict |
| Unk 912 | Pro 912 | conflict |
| Unk 913 | Ser 913 | conflict |
| Unk 914 | Leu 914 | conflict |
| Unk 915 | Val 915 | conflict |
| Unk 916 | His 916 | conflict |
| Unk 922 | Ala 922 | conflict |
| Unk 923 | Pro 923 | conflict |
| Unk 924 | Leu 924 | conflict |
| Unk 925 | Ala 925 | conflict |
| Unk 926 | Val 926 | conflict |
| Unk 927 | Leu 927 | conflict |
| Unk 928 | Arg 928 | conflict |
| Unk 929 | Ala 929 | conflict |
| Unk 930 | Phe 930 | conflict |
| Unk 931 | Lys 931 | conflict |
| Unk 932 | Val 932 | conflict |
| Unk 933 | Leu 933 | conflict |
| Unk 934 | Arg 934 | conflict |
| Unk 935 | Thr 935 | conflict |
| Unk 936 | Leu 936 | conflict |
| Unk 937 | Gly 937 | conflict |
| Unk 938 | Ser 938 | conflict |
| Unk 939 | Lys 939 | conflict |
| Unk 940 | Cys 940 | conflict |
| Unk 941 | Gly 941 | conflict |
| Unk 942 | Asp 942 | conflict |
| Unk 943 | Phe 943 | conflict |
| Unk 944 | Leu 944 | conflict |
| Unk 945 | Arg 945 | conflict |
| Unk 946 | Ser 946 | conflict |
| Unk 947 | Arg 947 | conflict |
| Unk 948 | Phe 948 | conflict |
| Unk 949 | Cys 949 | conflict |
| Unk 950 | Lys 950 | conflict |
| Unk 951 | Asp 951 | conflict |
| Unk 952 | Val 952 | conflict |
| Unk 953 | Leu 953 | conflict |
| Unk 954 | Pro 954 | conflict |
| Unk 955 | Lys 955 | conflict |
| Unk 956 | Leu 956 | conflict |
| Unk 957 | Ala 957 | conflict |
| Unk 958 | Gly 958 | conflict |
| Unk 959 | Ser 959 | conflict |
| Unk 977 | Thr 977 | conflict |
| Unk 978 | Leu 978 | conflict |
| Unk 979 | Ala 979 | conflict |
| Unk 980 | Phe 980 | conflict |
| Unk 981 | Lys 981 | conflict |
| Unk 982 | Leu 982 | conflict |
| Unk 983 | Gln 983 | conflict |
| Unk 984 | Leu 984 | conflict |
| Unk 985 | Ala 985 | conflict |
| Unk 986 | Val 986 | conflict |
| Unk 987 | Leu 987 | conflict |
| Unk 988 | Gln 988 | conflict |
| Unk 989 | Gly 989 | conflict |
| Unk 990 | Leu 990 | conflict |
| Unk 991 | Gly 991 | conflict |
| Unk 992 | Pro 992 | conflict |
| Unk 993 | Leu 993 | conflict |
| Unk 994 | Cys 994 | conflict |
| Unk 995 | Glu 995 | conflict |
| Unk 996 | Arg 996 | conflict |
| Unk 997 | Leu 997 | conflict |
| Unk 998 | Asp 998 | conflict |
| Unk 999 | Leu 999 | conflict |
| Unk 1000 | Gly 1000 | conflict |
| Unk 1001 | Glu 1001 | conflict |
| Unk 1002 | Gly 1002 | conflict |
| Unk 1003 | Asp 1003 | conflict |
| Unk 1021 | Val 1021 | conflict |
| Unk 1022 | Lys 1022 | conflict |
| Unk 1023 | Leu 1023 | conflict |
| Unk 1024 | Gln 1024 | conflict |
| Unk 1025 | Glu 1025 | conflict |
| Unk 1026 | Ala 1026 | conflict |
| Unk 1027 | Ala 1027 | conflict |
| Unk 1028 | Arg 1028 | conflict |
| Unk 1029 | Ser 1029 | conflict |
| Unk 1030 | Val 1030 | conflict |
| Unk 1031 | Phe 1031 | conflict |
| Unk 1032 | Leu 1032 | conflict |
| Unk 1033 | His 1033 | conflict |
| Unk 1034 | Leu 1034 | conflict |
| Unk 1035 | Met 1035 | conflict |
| Unk 1036 | Lys 1036 | conflict |
| Unk 1037 | Val 1037 | conflict |
| Unk 1038 | Asp 1038 | conflict |
| Unk 1039 | Pro 1039 | conflict |
| Unk 1040 | Asp 1040 | conflict |
| Unk 1041 | Ser 1041 | conflict |
| Unk 1042 | Thr 1042 | conflict |
| Unk 1043 | Trp 1043 | conflict |
| Unk 1044 | Phe 1044 | conflict |
| Unk 1045 | Leu 1045 | conflict |
| Unk 1046 | Leu 1046 | conflict |
| Unk 1047 | Asn 1047 | conflict |
| Unk 1048 | Glu 1048 | conflict |
| Unk 1049 | Leu 1049 | conflict |
| Unk 1050 | Tyr 1050 | conflict |
| Unk 1051 | Cys 1051 | conflict |
| Unk 1052 | Pro 1052 | conflict |
| Unk 1053 | Val 1053 | conflict |
| Unk 1054 | Gln 1054 | conflict |
| Unk 1055 | Phe 1055 | conflict |
| Unk 1056 | Thr 1056 | conflict |
| Unk 1057 | Pro 1057 | conflict |
| Unk 1058 | Pro 1058 | conflict |
| Unk 1059 | His 1059 | conflict |
| Unk 1060 | Pro 1060 | conflict |
| Unk 1061 | Ser 1061 | conflict |
| Unk 1062 | Leu 1062 | conflict |
| Unk 1063 | His 1063 | conflict |
| Unk 1064 | Pro 1064 | conflict |
| Unk 1065 | Val 1065 | conflict |
| Unk 1066 | Gln 1066 | conflict |
| Unk 1067 | Leu 1067 | conflict |
| Unk 1068 | His 1068 | conflict |
| Unk 1069 | Gly 1069 | conflict |
| Unk 1070 | Ala 1070 | conflict |
| Unk 1071 | Ser 1071 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 263915.6 | |
| All* | Total formula weight | 263915.6 |
