7F3P

Crystal structure of a nadp-dependent alcohol dehydrogenase mutant in apo form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	NADP-dependent isopropanol dehydrogenase	polymer	358	38513.7	4	UniProt (P14941) Pfam (PF08240) Pfam (PF00107) In PDB	Thermoanaerobacter brockii (Thermoanaerobium brockii)
2	A, B, C, D	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	C	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	1	Chemie (NAP)
4		water	water		18.0	228	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 352 (UniProt: P14941)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ser 84	Pro 84	engineered mutation
Leu 86	Ile 86	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	154054.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1005.0
All*	Total formula weight	155059.9

*Water molecules are not included.