7F3P
Crystal structure of a nadp-dependent alcohol dehydrogenase mutant in apo form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NADP-dependent isopropanol dehydrogenase | polymer | 358 | 38513.7 | 4 | UniProt (P14941) Pfam (PF08240) Pfam (PF00107) | Thermoanaerobacter brockii (Thermoanaerobium brockii) | |
| 2 | E, F, H, I (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | G (C) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 352 (UniProt: P14941)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 84 | Pro 84 | engineered mutation |
| Leu 86 | Ile 86 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 154054.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1005.0 | |
| All* | Total formula weight | 155059.9 |
