7F2L
Crystal structure of PDE4D catalytic domain complexed with compound 18a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 507 | 57859.5 | 2 | UniProt (Q08499) Pfam (PF18100) Pfam (PF00233) | Homo sapiens (Human) | DPDE3,PDE43 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, H (A, B) | (~{E})-4-[9-[(4-fluorophenyl)methoxy]-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-6-oxidanylidene-pyrano[3,2-b]xanthen-5-yl]oxybut-2-enoic acid | non-polymer | 600.6 | 2 | Chemie (1AS) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115719.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1380.7 | |
| All* | Total formula weight | 117099.7 |
