7F05

Crystal structure of human cardiac calsequestrin bound with calcium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, B, D	Calsequestrin-2	polymer	403	46800.6	4	UniProt (O14958) Pfam (PF01216) In PDB	Homo sapiens (Human)	Calsequestrin,cardiac muscle isoform
2	C, B, A, D	CALCIUM ION	non-polymer		40.1	74	Chemie (CA)
3		water	water		18.0	978	Chemie (HOH)

Sequence modifications

A, C, B, D: 20 - 399 (UniProt: O14958)

PDB	External Database	Details
Met -3	-	initiating methionine
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
Ser 7	-	expression tag
Ser 8	-	expression tag
Gly 9	-	expression tag
Leu 10	-	expression tag
Val 11	-	expression tag
Pro 12	-	expression tag
Arg 13	-	expression tag
Gly 14	-	expression tag
Ser 15	-	expression tag
His 16	-	expression tag
Met 17	-	expression tag
Ala 18	-	expression tag
Ser 19	-	expression tag
Glu 385	Ser 385	conflict
Glu 393	Ser 393	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	187202.4
Non-Polymers*	Number of molecules	74
	Total formula weight	2965.8
All*	Total formula weight	190168.2

*Water molecules are not included.