7EZF
Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36887.4 | 4 | UniProt (P09467) Pfam (PF00316) Pfam (PF18913) | Homo sapiens (Human) | FBPase 1,D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,Liver FBPase |
| 2 | E, G, I, K (A, B, C, D) | 7-chloranyl-5-ethyl-3-(3-hydroxy-3-oxopropyl)-1H-indole-2-carboxylic acid | non-polymer | 295.7 | 4 | Chemie (0KI) | |||
| 3 | F, H, J, L (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147549.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2543.3 | |
| All* | Total formula weight | 150093.1 |
