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7ERC

Crystal structure of human Biliverdin IX-beta reductase B with Deferasirox (ICL)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Flavin reductase (NADPH)polymer20622148.32UniProt (P30043)
Pfam (PF13460)
Homo sapiens (Human)FR,Biliverdin reductase B,BVR-B,Biliverdin-IX beta-reductase,Green heme-binding protein,GHBP,NADPH-dependent diaphorase,NADPH-flavin reductase,FLR
2C, F
(A, B)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.42Chemie (NAP)
3D
(A)
4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acidnon-polymer373.41Chemie (JBL)
4E
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
5G, H
(A, B)
waterwater18.0326Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight44296.7
Non-Polymers*Number of molecules4
Total formula weight1956.2
All*Total formula weight46252.9
*Water molecules are not included.

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PDB entries from 2025-06-25

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