7ER9
Crystal structure of human Biliverdin IX-beta reductase B with Febuxostat (TEI)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Flavin reductase (NADPH) | polymer | 216 | 23529.8 | 2 | UniProt (P30043) Pfam (PF13460) In PDB | Homo sapiens (Human) | FR,Biliverdin reductase B,BVR-B,Biliverdin-IX beta-reductase,Green heme-binding protein,GHBP,NADPH-dependent diaphorase,NADPH-flavin reductase,FLR |
2 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
3 | A, B | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID | non-polymer | 316.4 | 2 | Chemie (TEI) | |||
4 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
5 | water | water | 18.0 | 463 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 206 (UniProt: P30043)
PDB | External Database | Details |
---|---|---|
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47059.6 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2503.8 | |
All* | Total formula weight | 49563.5 |