7EPX

S protein of SARS-CoV-2 in complex with GW01

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Spike glycoprotein	polymer	1283	142530.7	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	H, I	heavy chain of GW01	polymer	457	49994.0	2		Homo sapiens (Human)
3	L, M	light chain of GW01	polymer	215	22681.9	2		Homo sapiens (Human)
4	a, b, c, d, D...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	23	In PDB GlyTouCan (G42666HT)
5	C, A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	25	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 1273 (UniProt: P0DTC2)

PDB	External Database	Details
Pro 817	Phe 817	engineered mutation
Pro 892	Ala 892	engineered mutation
Pro 899	Ala 899	engineered mutation
Pro 942	Ala 942	engineered mutation
Pro 986	Lys 986	engineered mutation
Pro 987	Val 987	engineered mutation
Leu 1274	-	expression tag
Glu 1275	-	expression tag
Asp 1276	-	expression tag
Tyr 1277	-	expression tag
Lys 1278	-	expression tag
Asp 1279	-	expression tag
Asp 1280	-	expression tag
Asp 1281	-	expression tag
Asp 1282	-	expression tag
Lys 1283	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	572943.8
Branched	Number of molecules	23
	Total formula weight	9761.2
Non-Polymers*	Number of molecules	25
	Total formula weight	5530.2
All*	Total formula weight	588235.2

*Water molecules are not included.