7EO8

Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C-like proteinase	polymer	306	33876.6	2	UniProt (P0C6U8) Pfam (PF05409)	Severe acute respiratory syndrome-related coronavirus (SARS-CoV)	main protease,3CL-PRO,3CLp,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2	C (A)	2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione	non-polymer		288.3	1	Chemie (FNO)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67753.3
Non-Polymers*	Number of molecules	1
	Total formula weight	288.3
All*	Total formula weight	68041.6

*Water molecules are not included.