7ENN

The structure of ALC1 bound to the nucleosome

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	K	Chromodomain-helicase-DNA-binding protein 1-like	polymer	897	101117.1	1	UniProt (Q86WJ1) Pfam (PF00176) Pfam (PF00271) In PDB	Homo sapiens (Human)	Amplified in liver cancer protein 1
2	A, E	Histone H3.2	polymer	135	15289.9	2	UniProt (P84233) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)
3	L, F	Histone H4	polymer	102	11263.2	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)
4	C, G	Histone H2A type 1	polymer	129	13978.2	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211) In PDB	Xenopus laevis (African clawed frog)
5	D, H	Histone H2B 1.1	polymer	122	13524.8	2	UniProt (P02281) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)	H2B1.1
6	I	DNA (167-MER)	polymer	167	51311.7	1		synthetic construct
7	J	DNA (167-MER)	polymer	167	51801.0	1		synthetic construct
8	K	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
9	K	BERYLLIUM TRIFLUORIDE ION	non-polymer		66.0	1	Chemie (BEF)

Sequence modifications

K: 1 - 897 (UniProt: Q86WJ1)

PDB	External Database	Details
Gln 857	Arg 857	engineered mutation

C, G: 1 - 129 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	conflict
Ser 123	Ala 124	conflict

D, H: 1 - 122 (UniProt: P02281)

PDB	External Database	Details
Thr 29	Ser 33	conflict

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	312342.0
Non-Polymers*	Number of molecules	2
	Total formula weight	493.2
All*	Total formula weight	312835.2

*Water molecules are not included.