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7ENJ

Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mediator of RNA polymerase II transcription subunit 1polymer1581168697.31UniProt (Q15648)
Pfam (PF10744)
Homo sapiens (Human)
2B
(B)
Unknown Chainpolymer201720.11Homo sapiens (Human)
3C
(D)
Mediator of RNA polymerase II transcription subunit 4polymer27029781.41UniProt (Q9NPJ6)
Pfam (PF10018)
Homo sapiens (Human)
4D
(F)
Mediator of RNA polymerase II transcription subunit 6polymer24628464.61UniProt (O75586)
Pfam (PF04934)
Homo sapiens (Human)
5E
(G)
Mediator of RNA polymerase II transcription subunit 7polymer23327285.31UniProt (O43513)
Pfam (PF05983)
Homo sapiens (Human)
6F
(H)
Isoform 2 of Mediator of RNA polymerase II transcription subunit 8polymer26829112.91UniProt (Q96G25)
Pfam (PF10232)
Homo sapiens (Human)
7G
(I)
Mediator of RNA polymerase II transcription subunit 9polymer14616422.81UniProt (Q9NWA0)
Pfam (PF07544)
Homo sapiens (Human)
8H
(J)
Mediator of RNA polymerase II transcription subunit 10polymer13515711.01UniProt (Q9BTT4)
Pfam (PF09748)
Homo sapiens (Human)
9I
(K)
Mediator of RNA polymerase II transcription subunit 11polymer11713145.81UniProt (Q9P086)
Pfam (PF10280)
Homo sapiens (Human)
10J
(N)
Mediator of RNA polymerase II transcription subunit 14polymer1454160787.61UniProt (O60244)
Pfam (PF08638)
Pfam (PF22981)
Pfam (PF22984)
Pfam (PF22983)
Homo sapiens (Human)
11K
(O)
Mediator of RNA polymerase II transcription subunit 15polymer78886830.11UniProt (Q96RN5)
Pfam (PF09606)
Pfam (PF21538)
Pfam (PF21539)
Homo sapiens (Human)
12L
(P)
Mediator of RNA polymerase II transcription subunit 16polymer87796908.11UniProt (Q9Y2X0)
Pfam (PF00400)
Pfam (PF11635)
Pfam (PF20718)
Pfam (PF20719)
Homo sapiens (Human)Mediator complex subunit 16,Thyroid hormone receptor-associated protein 5,Thyroid hormone receptor-associated protein complex 95 kDa component,Trap95,Vitamin D3 receptor-interacting protein complex 92 kDa component,DRIP92
13M
(Q)
Mediator of RNA polymerase II transcription subunit 17polymer65172984.01UniProt (Q9NVC6)
Pfam (PF10156)
Homo sapiens (Human)
14N
(R)
Mediator of RNA polymerase II transcription subunit 18polymer20823693.71UniProt (Q9BUE0)
Pfam (PF09637)
Homo sapiens (Human)
15O
(S)
Mediator of RNA polymerase II transcription subunit 19polymer24426321.11UniProt (A0JLT2)
Pfam (PF10278)
Homo sapiens (Human)
16P
(T)
Mediator of RNA polymerase II transcription subunit 20polymer21223243.81UniProt (Q9H944)
Pfam (PF08612)
Homo sapiens (Human)
17Q
(U)
Mediator of RNA polymerase II transcription subunit 21polymer14415575.21UniProt (Q13503)
Pfam (PF11221)
Homo sapiens (Human)
18R
(V)
Mediator of RNA polymerase II transcription subunit 22polymer20022243.71UniProt (Q15528)
Pfam (PF06179)
Homo sapiens (Human)
19S
(W)
Mediator of RNA polymerase II transcription subunit 23polymer1368156652.21UniProt (Q9ULK4)
Pfam (PF11573)
Homo sapiens (Human)
20T
(X)
Mediator of RNA polymerase II transcription subunit 24polymer989110430.21UniProt (O75448)
Pfam (PF11277)
Homo sapiens (Human)
21U
(Z)
Mediator of RNA polymerase II transcription subunit 26polymer60065544.41UniProt (O95402)
Pfam (PF08711)
Pfam (PF15694)
Pfam (PF15693)
Homo sapiens (Human)
22V
(0)
Mediator of RNA polymerase II transcription subunit 27polymer31135478.71UniProt (Q6P2C8)
Pfam (PF11571)
Homo sapiens (Human)
23W
(1)
Mediator of RNA polymerase II transcription subunit 28polymer17819540.11UniProt (Q9H204)
Pfam (PF11594)
Homo sapiens (Human)
24X
(2)
Mediator of RNA polymerase II transcription subunit 29polymer20021089.81UniProt (Q9NX70)
Pfam (PF11568)
Homo sapiens (Human)
25Y
(3)
Mediator of RNA polymerase II transcription subunit 30polymer17820301.21UniProt (Q96HR3)
Pfam (PF11315)
Homo sapiens (Human)
26Z
(4)
Mediator of RNA polymerase II transcription subunit 31polymer13115826.11UniProt (Q9Y3C7)
Pfam (PF05669)
Homo sapiens (Human)
27AA
(0)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains26
Total formula weight1303791.4
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight1303856.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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