7END
Crystal structure of SARS-CoV 3CLpro in complex with the non-covalent inhibitor WU-04
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Replicase polyprotein 1a | polymer | 306 | 33876.6 | 1 | UniProt (P0C6U8) Pfam (PF05409) UniProt (by SIFTS) (P0C6X7) | Human SARS coronavirus (SARS-CoV) | pp1a,ORF1a polyprotein |
| 2 | B (A) | ~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide | non-polymer | 526.4 | 1 | Chemie (J7R) | |||
| 3 | C (A) | water | water | 18.0 | 261 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33876.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 526.4 | |
| All* | Total formula weight | 34403.0 |
