7EMG

Carbonyl Reductase Variant 4 (R123C/L209P/F183Y/V61K) from Serratia marcescens complexed with NADP+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3-oxoacyl-[acyl-carrier-protein] reductase	polymer	252	26624.4	2	UniProt (A0A0G8B235)	Serratia marcescens
2	C, E (A, B)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
3	D (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	F, G (A, B)	water	water		18.0	58	Chemie (HOH)

Sequence modifications

A, B: 1 - 244 (UniProt: A0A0G8B235)

PDB	External Database	Details
Met -7	-	initiating methionine
Gly -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Lys 61	Val 61	engineered mutation
Cys 123	Arg 123	engineered mutation
Tyr 183	Phe 183	engineered mutation
Pro 209	Leu 209	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53248.9
Non-Polymers*	Number of molecules	3
	Total formula weight	1552.9
All*	Total formula weight	54801.8

*Water molecules are not included.