7EKT
human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124 and PNU-120596
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Neuronal acetylcholine receptor subunit alpha-7 | polymer | 502 | 56505.2 | 5 | UniProt (P36544) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (Human) | |
| 2 | F, G, H, I, J (F, G, H, I, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 3 | CA, K, Q, U, Y (E, A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 4 | DA, L, R, V, Z (E, A, B, C, D) | CHOLESTEROL | non-polymer | 386.7 | 5 | Chemie (CLR) | |||
| 5 | AA, M, O, S, W (E, A, B, C, D) | 7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide | non-polymer | 320.8 | 5 | Chemie (I33) | |||
| 6 | BA, N, P, T, X (E, A, B, C, D) | N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea | non-polymer | 311.7 | 5 | Chemie (I34) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 282525.9 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2122.0 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 6202.1 | |
| All* | Total formula weight | 290850.0 |
