7EJV
The co-crystal structure of DYRK2 with YK-2-69
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | polymer | 387 | 44655.5 | 1 | UniProt (Q92630) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (B) | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | polymer | 391 | 45174.2 | 1 | UniProt (Q92630) Pfam (PF00069) | Homo sapiens (human) | |
| 3 | C, D (A, B) | [6-[[4-[2-(dimethylamino)-1,3-benzothiazol-6-yl]-5-fluoranyl-pyrimidin-2-yl]amino]pyridin-3-yl]-(4-ethylpiperazin-1-yl)methanone | non-polymer | 506.6 | 2 | Chemie (YK2) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89829.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1013.2 | |
| All* | Total formula weight | 90842.8 |
