7EJJ
Crystal structure of KRED F147L/L153Q/Y190P variant and methyl methacrylate complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase | polymer | 250 | 26493.9 | 4 | UniProt (Q6WVP7) | Lactobacillus kefiri | NADPH dependent R-specific alcohol dehydrogenase,SDR family NAD(P)-dependent oxidoreductase |
| 2 | E, H, J, M (A, B, C, D) | methyl 2-methylprop-2-enoate | non-polymer | 100.1 | 4 | Chemie (J69) PubChem (6658) | |||
| 3 | F, I, K, N (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 4 | G, L (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 799 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 252 (UniProt: Q6WVP7)
| PDB | External Database | Details |
|---|---|---|
| Leu 147 | Phe 147 | engineered mutation |
| Gln 153 | Leu 153 | engineered mutation |
| Pro 190 | Tyr 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 105975.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3422.7 | |
| All* | Total formula weight | 109398.4 |
