7EIY
Human histidine decarboxylase mutant Y334F soaking with histidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histidine decarboxylase | polymer | 481 | 54314.2 | 2 | UniProt (P19113) Pfam (PF00282) | Homo sapiens (Human) | HDC |
| 2 | C, F (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 3 | D, G (A, B) | HISTIDINE | non-polymer | 156.2 | 2 | Chemie (HIS) | |||
| 4 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 477 (UniProt: P19113)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 180 | Cys 180 | engineered mutation |
| Ser 418 | Cys 418 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 108628.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 902.7 | |
| All* | Total formula weight | 109531.0 |
