7EID

Crystal structure of AF9 YEATS domain in complex with H4K8acK12ac peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein AF-9	polymer	145	16848.4	2	UniProt (P42568) Pfam (PF03366) In PDB	Homo sapiens (Human)	ALL1-fused gene from chromosome 9 protein,Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein,YEATS domain-containing protein 3
2	C, D	Histone H4	polymer	10	943.1	2	UniProt (by SIFTS) (P62805) In PDB	Homo sapiens
3	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	271	Chemie (HOH)

Sequence modifications

A, B: 1 - 138 (UniProt: P42568)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	35582.9
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	35767.1

*Water molecules are not included.