7EI2
Structure of human NNMT in complex with macrocyclic peptide 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nicotinamide N-methyltransferase | polymer | 259 | 28891.2 | 1 | UniProt (P40261) Pfam (PF01234) | Homo sapiens (Human) | |
| 2 | B (B) | macrocyclic peptide 8 | polymer | 9 | 1175.4 | 1 | synthetic construct | ||
| 3 | C, D (A, B) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
A: 3 - 260 (UniProt: P40261)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Ala 103 | Glu 103 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30066.5 | |
| All* | Total formula weight | 30066.5 |






