7EHV
Human MTHFD2 in complex with compound 21 and 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial | polymer | 315 | 34183.6 | 2 | UniProt (P13995) Pfam (PF00763) Pfam (PF02882) | Homo sapiens (Human) | |
| 2 | C, E (A, B) | 1-(3,4-dichlorobenzyl)-8-(((1R,4R)-4-hydroxycyclohexyl)amino)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione | non-polymer | 452.3 | 2 | Chemie (J4L) | |||
| 3 | D, F (A, B) | (2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acid | non-polymer | 418.4 | 2 | Chemie (J49) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68367.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1741.4 | |
| All* | Total formula weight | 70108.5 |
