7EFQ
Crystal structure of hPPARgamma ligand binding domain complexed with rosiglitazone-based fluorescence probe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31449.5 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | C (A) | (5S)-5-[[4-[2-[[7-(diethylamino)-2-oxidanylidene-chromen-4-yl]-methyl-amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione | non-polymer | 495.6 | 1 | Chemie (J3F) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, B: 204 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
| Ala 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62899.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 495.6 | |
| All* | Total formula weight | 63394.6 |
