7EFL
Crystal structure of the gastric proton pump K791S in (BYK)E2BeF state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium/potassium-transporting ATPase subunit alpha | polymer | 987 | 109220.6 | 1 | UniProt (A0A5G2QYH2) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) UniProt (by SIFTS) (P19156) | Sus scrofa (Pig) | |
| 2 | B (B) | Potassium-transporting ATPase subunit beta | polymer | 255 | 28976.2 | 1 | UniProt (P18434) Pfam (PF00287) | Sus scrofa (Pig) | Gastric H(+)/K(+) ATPase subunit beta,Proton pump beta chain,gp60-90 |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E, F, J (A, B) | RUBIDIUM ION | non-polymer | 85.5 | 4 | Chemie (RB) | |||
| 5 | G (A) | (7R,8R,9S)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridine-7,8-diol | non-polymer | 309.4 | 1 | Chemie (J3C) | |||
| 6 | H, I (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | K (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 48 - 1033 (UniProt: A0A5G2QYH2)
B: 37 - 290 (UniProt: P18434)
| PDB | External Database | Details |
|---|---|---|
| Gly 47 | - | expression tag |
| Ser 791 | Lys 799 | engineered mutation |
| Ser 1005 | Gly 1013 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 36 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 138196.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1118.0 | |
| All* | Total formula weight | 139314.7 |
