7EF9
Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form II)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenine DNA glycosylase | polymer | 448 | 50109.8 | 1 | UniProt (Q99P21) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) Pfam (PF14815) | Mus musculus (Mouse) | MutY homolog,mMYH |
| 2 | B (B) | DNA (5'-D(*AP*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3') | polymer | 14 | 4385.9 | 1 | Homo sapiens | ||
| 3 | C (C) | DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3') | polymer | 14 | 4082.6 | 1 | Homo sapiens | ||
| 4 | D (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 5 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F, H, I, J, K... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 7 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | M, N, O (A, B, C) | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A: 45 - 487 (UniProt: Q99P21)
| PDB | External Database | Details |
|---|---|---|
| Gly 40 | - | expression tag |
| Pro 41 | - | expression tag |
| Gly 42 | - | expression tag |
| Tyr 43 | - | expression tag |
| Gln 44 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58578.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1085.5 | |
| All* | Total formula weight | 59663.9 |
