7EDH
Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), one RBD-up conformation 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1286 | 142662.8 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | AA, BA, CA, D, DA... (a, b, c, D, d...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 29 | In PDB GlyTouCan (G42666HT) | |||
| 3 | N (N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | HA, IA, JA, KA, LA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) |
Sequence modifications
A, B, C: 16 - 1205 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| Glu -4 | - | expression tag |
| Thr -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Thr -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Trp 3 | - | expression tag |
| Val 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Leu 6 | - | expression tag |
| Leu 7 | - | expression tag |
| Trp 8 | - | expression tag |
| Val 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Thr 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Asp 15 | - | expression tag |
| - | His 69 | deletion |
| - | Val 70 | deletion |
| - | Tyr 144 | deletion |
| Tyr 498 | Asn 501 | conflict |
| Asp 567 | Ala 570 | conflict |
| Gly 611 | Asp 614 | conflict |
| His 678 | Pro 681 | conflict |
| Ala 680 | Arg 683 | conflict |
| Ala 682 | Arg 685 | conflict |
| Ile 713 | Thr 716 | conflict |
| Ala 979 | Ser 982 | conflict |
| Pro 983 | Lys 986 | conflict |
| Pro 984 | Val 987 | conflict |
| His 1115 | Asp 1118 | conflict |
| Glu 1206 | - | expression tag |
| Phe 1207 | - | expression tag |
| Gly 1208 | - | expression tag |
| Ser 1209 | - | expression tag |
| Gly 1210 | - | expression tag |
| Gly 1211 | - | expression tag |
| Tyr 1212 | - | expression tag |
| Ile 1213 | - | expression tag |
| Pro 1214 | - | expression tag |
| Glu 1215 | - | expression tag |
| Ala 1216 | - | expression tag |
| Pro 1217 | - | expression tag |
| Arg 1218 | - | expression tag |
| Asp 1219 | - | expression tag |
| Gly 1220 | - | expression tag |
| Gln 1221 | - | expression tag |
| Ala 1222 | - | expression tag |
| Tyr 1223 | - | expression tag |
| Val 1224 | - | expression tag |
| Arg 1225 | - | expression tag |
| Lys 1226 | - | expression tag |
| Asp 1227 | - | expression tag |
| Gly 1228 | - | expression tag |
| Glu 1229 | - | expression tag |
| Trp 1230 | - | expression tag |
| Val 1231 | - | expression tag |
| Leu 1232 | - | expression tag |
| Leu 1233 | - | expression tag |
| Ser 1234 | - | expression tag |
| Thr 1235 | - | expression tag |
| Phe 1236 | - | expression tag |
| Leu 1237 | - | expression tag |
| Lys 1238 | - | expression tag |
| Gly 1239 | - | expression tag |
| Gln 1240 | - | expression tag |
| Asp 1241 | - | expression tag |
| Asn 1242 | - | expression tag |
| Ser 1243 | - | expression tag |
| Ala 1244 | - | expression tag |
| Asp 1245 | - | expression tag |
| Ile 1246 | - | expression tag |
| Gln 1247 | - | expression tag |
| His 1248 | - | expression tag |
| Ser 1249 | - | expression tag |
| Gly 1250 | - | expression tag |
| Arg 1251 | - | expression tag |
| Pro 1252 | - | expression tag |
| Leu 1253 | - | expression tag |
| Glu 1254 | - | expression tag |
| Ser 1255 | - | expression tag |
| Arg 1256 | - | expression tag |
| Gly 1257 | - | expression tag |
| Pro 1258 | - | expression tag |
| Phe 1259 | - | expression tag |
| Glu 1260 | - | expression tag |
| Gln 1261 | - | expression tag |
| Lys 1262 | - | expression tag |
| Leu 1263 | - | expression tag |
| Ile 1264 | - | expression tag |
| Ser 1265 | - | expression tag |
| Glu 1266 | - | expression tag |
| Glu 1267 | - | expression tag |
| Asp 1268 | - | expression tag |
| Leu 1269 | - | expression tag |
| Asn 1270 | - | expression tag |
| Met 1271 | - | expression tag |
| His 1272 | - | expression tag |
| Thr 1273 | - | expression tag |
| Gly 1274 | - | expression tag |
| His 1275 | - | expression tag |
| His 1276 | - | expression tag |
| His 1277 | - | expression tag |
| His 1278 | - | expression tag |
| His 1279 | - | expression tag |
| His 1280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 427988.4 | |
| Branched | Number of molecules | 30 |
| Total formula weight | 12894.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3539.3 | |
| All* | Total formula weight | 444421.9 |
