7E8E
CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex, transmembrane and intracellular region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (G, E) | Kv channel-interacting protein 1 | polymer | 181 | 21242.9 | 2 | UniProt (Q9NZI2) Pfam (PF13833) Pfam (PF13499) | Homo sapiens (Human) | KChIP1,A-type potassium channel modulatory protein 1,Potassium channel-interacting protein 1,Vesicle APC-binding protein |
| 2 | B, E, H, K (C, D, A, B) | Potassium voltage-gated channel subfamily D member 2 | polymer | 494 | 55755.7 | 4 | UniProt (Q9NZV8) Pfam (PF11601) Pfam (PF02214) Pfam (PF00520) Pfam (PF07885) Pfam (PF11879) | Homo sapiens (Human) | Voltage-gated potassium channel subunit Kv4.2 |
| 3 | C, I (K, I) | Dipeptidyl aminopeptidase-like protein 6 | polymer | 31 | 3032.8 | 2 | UniProt (P42658) | Homo sapiens (Human) | DPPX,Dipeptidyl aminopeptidase-related protein,Dipeptidyl peptidase 6,Dipeptidyl peptidase IV-like protein,Dipeptidyl peptidase VI,DPP VI |
| 4 | D, J (H, F) | Kv channel-interacting protein 1 | polymer | 180 | 21145.8 | 2 | UniProt (Q9NZI2) Pfam (PF13833) Pfam (PF13499) | Homo sapiens (Human) | KChIP1,A-type potassium channel modulatory protein 1,Potassium channel-interacting protein 1,Vesicle APC-binding protein |
| 5 | F, L (L, J) | Dipeptidyl aminopeptidase-like protein 6 | polymer | 28 | 2819.6 | 2 | UniProt (P42658) | Homo sapiens (Human) | DPPX,Dipeptidyl aminopeptidase-related protein,Dipeptidyl peptidase 6,Dipeptidyl peptidase IV-like protein,Dipeptidyl peptidase VI,DPP VI |
Sequence modifications
C, D, A, B: 2 - 495 (UniProt: Q9NZV8)
K, I: 32 - 58 (UniProt: P42658)
L, J: 32 - 58 (UniProt: P42658)
| PDB | External Database | Details |
|---|---|---|
| Ser 450 | Asn 450 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | - | expression tag |
| Ala 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Ala 31 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 31 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 319505.3 | |
| All* | Total formula weight | 319505.3 |
