7E6T
Structural insights into the activation of human calcium-sensing receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Extracellular calcium-sensing receptor | polymer | 862 | 97326.1 | 2 | UniProt (P41180) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) | Homo sapiens (Human) | CaR,CaSR,hCasR,Parathyroid cell calcium-sensing receptor 1,PCaR1 |
| 2 | C, J (B, A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | D, E, F, K, L... (B, A) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | G, H, N, O (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | I, P (B, A) | CYCLOMETHYLTRYPTOPHAN | non-polymer | 216.2 | 2 | Chemie (TCR) |
Sequence modifications
B, A: 20 - 870 (UniProt: P41180)
| PDB | External Database | Details |
|---|---|---|
| Ala 871 | - | expression tag |
| Ala 872 | - | expression tag |
| Ala 873 | - | expression tag |
| Asp 874 | - | expression tag |
| Tyr 875 | - | expression tag |
| Lys 876 | - | expression tag |
| Asp 877 | - | expression tag |
| Asp 878 | - | expression tag |
| Asp 879 | - | expression tag |
| Asp 880 | - | expression tag |
| Lys 881 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 194652.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1747.7 | |
| All* | Total formula weight | 196399.9 |
