7E62

Mouse TAB2 NZF in complex with Lys6-linked diubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, H)	ubiquitin	polymer	76	8604.8	2	UniProt (P62983) Pfam (PF00240)	Mus musculus (Mouse)
2	B, E (B, I)	Ubiquitin	polymer	77	8691.9	2	UniProt (P62983) Pfam (PF00240)	Mus musculus (Mouse)
3	C, F (C, J)	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2	polymer	55	6195.0	2	UniProt (Q99K90)	Mus musculus (Mouse)	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2,TAK1-binding protein 2,TAB-2,TGF-beta-activated kinase 1-binding protein 2
4	G (A)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
5	H, I (C, J)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6	J, K, L, M, N... (A, B, C, H, I...)	water	water		18.0	48	Chemie (HOH)

Sequence modifications

A, H: 1 - 76 (UniProt: P62983)

PDB	External Database	Details
Arg 6	Lys 6	engineered mutation

B, I: 1 - 77 (UniProt: P62983)

PDB	External Database	Details
Asp 77	Ala 77	engineered mutation

C, J: 644 - 693 (UniProt: Q99K90)

PDB	External Database	Details
Gly 639	-	expression tag
Pro 640	-	expression tag
Leu 641	-	expression tag
Gly 642	-	expression tag
Ser 643	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	46983.5
Non-Polymers*	Number of molecules	3
	Total formula weight	369.1
All*	Total formula weight	47352.6

*Water molecules are not included.