7E45
Crystal structure of compound 7 bound to MIF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 114 | 12355.1 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (Human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
| 2 | D, E, F, G, H... (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 13 | Chemie (CL) | |||
| 3 | N (B) | (2R)-7-[(2R,3R,4R,5S,6S)-6-(hydroxymethyl)-3-[(2R,3R,4R,5R,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-2-(4-methoxy-3-oxidanyl-phenyl)-5-oxidanyl-2,3-dihydrochromen-4-one | non-polymer | 610.6 | 1 | Chemie (HWO) | |||
| 4 | R, S, T (A, B, C) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37065.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1071.5 | |
| All* | Total formula weight | 38136.6 |
