7E3W

Metallo beta-lactamase fold protein (cAMP bound)

Replaces:  6L7G

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	UPF0173 metal-dependent hydrolase C7P97_11315	polymer	246	27216.7	6	UniProt (W8UA39) Pfam (PF12706) UniProt (by SIFTS) (Q2FXM0)	Staphylococcus aureus
2	EA, G, JA, N, S... (E, A, F, B, C...)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	6	Chemie (CMP)
3	H, Y (A, D)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
4	I, Z (A, D)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	AA, BA, FA, GA, J... (D, E, A, F, B...)	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
6	CA, DA, HA, IA, L... (D, E, A, F, B...)	NICKEL (II) ION	non-polymer		58.7	12	Chemie (NI)
7	OA, PA, QA, RA, SA... (A, B, C, D, E...)	water	water		18.0	727	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 229 (UniProt: W8UA39)

PDB	External Database	Details
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	163300.4
Non-Polymers*	Number of molecules	34
	Total formula weight	3779.7
All*	Total formula weight	167080.1

*Water molecules are not included.