7E3G
Crystal structure of Trypanosoma brucei cathepsin B R91C/T223C mutant in the living cell
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cysteine peptidase C (CPC) | polymer | 340 | 37207.7 | 1 | UniProt (D6XHE1) Pfam (PF00112) In PDB | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) | |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 1 - 340 (UniProt: D6XHE1)
| PDB | External Database | Details |
|---|---|---|
| Cys 91 | Arg 91 | engineered mutation |
| Cys 223 | Thr 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37207.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| All* | Total formula weight | 38218.6 |
