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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7E32

Serotonin 1D (5-HT1D) receptor-Gi protein complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440414.01UniProt (P63096)
Pfam (PF00503)		Homo sapiens (Human)Adenylate cyclase-inhibiting G alpha protein
2B
(B)		Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34537915.51UniProt (P62873)
Pfam (PF25391)		Homo sapiens (Human)Transducin beta chain 1
3C
(E)		scFv16polymer24826466.51Mus musculus (mouse)
4D
(G)		Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)		Homo sapiens (Human)G gamma-I
5E
(R)		Soluble cytochrome b562,5-hydroxytryptamine receptor 1Dpolymer51657748.21UniProt (P0ABE7)
UniProt (P28221)
Pfam (PF00001)		Escherichia coliCytochrome b-562,5-HT-1D,5-HT1D,Serotonin 1D alpha receptor,5-HT-1D-alpha,Serotonin receptor 1D
6F
(R)		SEROTONINnon-polymer176.21Chemie (SRO)
7G
(R)		CHOLESTEROLnon-polymer386.71Chemie (CLR)
PubChem (16219173)
PubChem (16758052)
PubChem (304)
PubChem (176980071)
PubChem (40477506)
PubChem (40557614)
PubChem (42579431)
PubChem (42579432)
PubChem (18640088)
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PubChem (1715244)
PubChem (45044259)
PubChem (23423981)
PubChem (49853509)
PubChem (50990013)
PubChem (52934537)
PubChem (56621683)
PubChem (191463)
PubChem (57915018)
PubChem (57939063)
PubChem (58428240)
PubChem (58445498)
PubChem (58663286)
PubChem (368063)
PubChem (369319)
PubChem (44654663)
PubChem (59450329)
PubChem (59628412)
PubChem (59965215)
PubChem (71234641)
PubChem (59993755)
PubChem (60001463)
PubChem (66634651)
PubChem (68055877)
PubChem (68166463)
PubChem (68315613)
PubChem (46937002)
PubChem (70795838)
PubChem (70797612)
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PubChem (71463909)
PubChem (638019)
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PubChem (1549081)
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PubChem (68311425)
PubChem (68311398)
PubChem (143173313)
PubChem (177156123)
PubChem (89951918)
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PubChem (5997)
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PubChem (6432564)
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PubChem (124146240)
PubChem (7059399)
PubChem (124897607)
PubChem (124896959)
PubChem (6419195)
PubChem (10861996)
PubChem (132837164)
PubChem (101624109)
PubChem (6994560)
PubChem (7055705)
PubChem (7055706)
PubChem (7059398)
PubChem (7059400)
PubChem (7059635)
PubChem (7103033)
PubChem (7182477)
PubChem (7182478)
PubChem (11834483)
PubChem (11888915)
PubChem (11888914)
PubChem (9909206)
PubChem (10045721)
PubChem (71168115)
PubChem (10134774)
PubChem (10293553)
PubChem (71173031)
PubChem (124225449)
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PubChem (11003580)
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PubChem (11868624)
PubChem (11868625)
PubChem (11869366)
PubChem (11869367)
PubChem (11869368)
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PubChem (12120344)
PubChem (12156156)
PubChem (12303135)
PubChem (12303148)
PubChem (12303156)
PubChem (12303159)
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PubChem (15939944)
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PubChem (124909225)
PubChem (171828367)
PubChem (173516975)
PubChem (130459183)
PubChem (131992107)
PubChem (139568882)
PubChem (142983773)
PubChem (144054483)
PubChem (144209461)
PubChem (144331236)
PubChem (144808354)
PubChem (145053568)
PubChem (145157652)
PubChem (145215073)
PubChem (145230478)
PubChem (146320991)
PubChem (147857230)
PubChem (154993519)
PubChem (158603858)
PubChem (162906452)
PubChem (162906453)
PubChem (162906454)
PubChem (162906455)
PubChem (162906456)
PubChem (162906457)
PubChem (163255768)
PubChem (163389210)
PubChem (164665303)
PubChem (166553771)
PubChem (166712004)
PubChem (170116175)
PubChem (171764280)
PubChem (171817101)
PubChem (171817104)
PubChem (174285573)
Sequence modifications
A: 1 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Asn 47Ser 47engineered mutation
Ala 203Gly 203engineered mutation
Ala 245Glu 245engineered mutation
Ser 326Ala 326engineered mutation
B: 2 - 340 (UniProt: P62873)
PDBExternal DatabaseDetails
Met -4-initiating methionine
Gly -3-expression tag
Ser -2-expression tag
Leu -1-expression tag
Leu 0-expression tag
Gln 1-expression tag
R: -115 - -10 (UniProt: P0ABE7)
PDBExternal DatabaseDetails
Asp -138-expression tag
Tyr -137-expression tag
Lys -136-expression tag
Asp -135-expression tag
Asp -134-expression tag
Asp -133-expression tag
Asp -132-expression tag
Ala -131-expression tag
Lys -130-expression tag
Leu -129-expression tag
Gln -128-expression tag
Thr -127-expression tag
Met -126-expression tag
His -125-expression tag
His -124-expression tag
His -123-expression tag
His -122-expression tag
His -121-expression tag
His -120-expression tag
His -119-expression tag
His -118-expression tag
His -117-expression tag
His -116-expression tag
Trp -109Met 29engineered mutation
Ile -14His 124engineered mutation
Leu -10Arg 128engineered mutation
Ala -9-linker
Ser -8-linker
Glu -7-linker
Asn -6-linker
Leu -5-linker
Tyr -4-linker
Phe -3-linker
Gln -2-linker
Gly -1-linker
Gly 0-linker
Thr 1-linker
R: 2 - 377 (UniProt: P28221)
PDBExternal DatabaseDetails
Trp 127Leu 127engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight170405.4
Non-Polymers*Number of molecules2
Total formula weight562.9
All*Total formula weight170968.2
*Water molecules are not included.

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PDB entries from 2026-05-06

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