7E24
Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Oxidoreductase | polymer | 251 | 27454.1 | 4 | UniProt (Q6BDS0) Pfam (PF00106) | Exiguobacterium acetylicum | |
| 2 | E, F, G, H (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 249 (UniProt: Q6BDS0)
| PDB | External Database | Details |
|---|---|---|
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Leu 82 | Trp 82 | engineered mutation |
| Val 88 | Phe 88 | engineered mutation |
| Ala 121 | Val 121 | engineered mutation |
| Leu 138 | Ala 138 | engineered mutation |
| Met 142 | Arg 142 | engineered mutation |
| Val 190 | Ala 190 | engineered mutation |
| Ala 193 | Ser 193 | engineered mutation |
| Phe 201 | Tyr 201 | engineered mutation |
| Ala 204 | Asn 204 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 109816.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2973.6 | |
| All* | Total formula weight | 112790.0 |
