7E21
Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state with ATP-gamma-S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Sodium/potassium-transporting ATPase subunit alpha-1 | polymer | 1023 | 113012.8 | 1 | UniProt (P05023) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00689) In PDB | Homo sapiens (human) | Na(+)/K(+) ATPase alpha-1 subunit,Sodium pump subunit alpha-1 |
| 2 | B | Sodium/potassium-transporting ATPase subunit beta-1 | polymer | 303 | 35108.3 | 1 | UniProt (P05026) Pfam (PF00287) In PDB | Homo sapiens (human) | Sodium/potassium-dependent ATPase subunit beta-1 |
| 3 | C | Sodium/potassium-transporting ATPase subunit gamma | polymer | 66 | 7292.3 | 1 | UniProt (P54710) Pfam (PF02038) In PDB | Homo sapiens (human) | Na(+)/K(+) ATPase subunit gamma,FXYD domain-containing ion transport regulator 2,Sodium pump gamma chain |
| 4 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | A | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | A | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 1 | Chemie (AGS) | |||
| 8 | A, B, C | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 6 | Chemie (Y01) | |||
| 9 | A, B | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) | |||
| 10 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 11 | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 155413.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 5361.4 | |
| All* | Total formula weight | 161199.2 |
