7E0U
Crystal Structure of Human Indoleamine 2,3-dioxygenagse 1 (hIDO1) Complexed with 6-Bromo-N-(((1S,2S)-2-chlorocyclohexyl)methyl)-1H-indazol-4-amine (39)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Indoleamine 2,3-dioxygenase 1 | polymer | 392 | 44126.7 | 2 | UniProt (P14902) Pfam (PF01231) | Homo sapiens (Human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
| 2 | C, E (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, F (A, B) | 6-bromanyl-~{N}-[[(1~{S},2~{S})-2-chloranylcyclohexyl]methyl]-1~{H}-indazol-4-amine | non-polymer | 342.7 | 2 | Chemie (HUC) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A, B: 12 - 403 (UniProt: P14902)
| PDB | External Database | Details |
|---|---|---|
| Glu 374 | Leu 374 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88253.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1918.3 | |
| All* | Total formula weight | 90171.7 |
