7DZX
Spike protein from SARS-CoV2 with Fab fragment of enhancing antibody 8D2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1249 | 138320.9 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | D (H) | Fab Heavy chain of enhancing antibody | polymer | 227 | 24330.1 | 1 | Homo sapiens (Human) | ||
| 3 | E (L) | Fab light chain of enhancing antibody | polymer | 213 | 23194.7 | 1 | Homo sapiens (Human) |
Sequence modifications
A, B, C: 27 - 1147 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gln 14 | - | expression tag |
| Cys 15 | - | expression tag |
| Val 16 | - | expression tag |
| Asn 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Thr 19 | - | expression tag |
| Thr 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Thr 22 | - | expression tag |
| Gln 23 | - | expression tag |
| Leu 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Pro 26 | - | expression tag |
| Gly 614 | Asp 614 | engineered mutation |
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Gly 685 | Arg 685 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
| Phe 1148 | - | expression tag |
| Lys 1149 | - | expression tag |
| Glu 1150 | - | expression tag |
| Glu 1151 | - | expression tag |
| Leu 1152 | - | expression tag |
| Asp 1153 | - | expression tag |
| Lys 1154 | - | expression tag |
| Tyr 1155 | - | expression tag |
| Phe 1156 | - | expression tag |
| Lys 1157 | - | expression tag |
| Asn 1158 | - | expression tag |
| His 1159 | - | expression tag |
| Thr 1160 | - | expression tag |
| Ser 1161 | - | expression tag |
| Pro 1162 | - | expression tag |
| Asp 1163 | - | expression tag |
| Val 1164 | - | expression tag |
| Asp 1165 | - | expression tag |
| Leu 1166 | - | expression tag |
| Gly 1167 | - | expression tag |
| Asp 1168 | - | expression tag |
| Ile 1169 | - | expression tag |
| Ser 1170 | - | expression tag |
| Gly 1171 | - | expression tag |
| Ile 1172 | - | expression tag |
| Asn 1173 | - | expression tag |
| Ala 1174 | - | expression tag |
| Ser 1175 | - | expression tag |
| Val 1176 | - | expression tag |
| Val 1177 | - | expression tag |
| Asn 1178 | - | expression tag |
| Ile 1179 | - | expression tag |
| Gln 1180 | - | expression tag |
| Lys 1181 | - | expression tag |
| Glu 1182 | - | expression tag |
| Ile 1183 | - | expression tag |
| Asp 1184 | - | expression tag |
| Arg 1185 | - | expression tag |
| Leu 1186 | - | expression tag |
| Asn 1187 | - | expression tag |
| Glu 1188 | - | expression tag |
| Val 1189 | - | expression tag |
| Ala 1190 | - | expression tag |
| Lys 1191 | - | expression tag |
| Asn 1192 | - | expression tag |
| Leu 1193 | - | expression tag |
| Asn 1194 | - | expression tag |
| Glu 1195 | - | expression tag |
| Ser 1196 | - | expression tag |
| Leu 1197 | - | expression tag |
| Ile 1198 | - | expression tag |
| Asp 1199 | - | expression tag |
| Leu 1200 | - | expression tag |
| Gln 1201 | - | expression tag |
| Glu 1202 | - | expression tag |
| Leu 1203 | - | expression tag |
| Gly 1204 | - | expression tag |
| Lys 1205 | - | expression tag |
| Tyr 1206 | - | expression tag |
| Glu 1207 | - | expression tag |
| Gln 1208 | - | expression tag |
| Tyr 1209 | - | expression tag |
| Ile 1210 | - | expression tag |
| Lys 1211 | - | expression tag |
| Gly 1212 | - | expression tag |
| Ser 1213 | - | expression tag |
| Gly 1214 | - | expression tag |
| Arg 1215 | - | expression tag |
| Glu 1216 | - | expression tag |
| Asn 1217 | - | expression tag |
| Leu 1218 | - | expression tag |
| Tyr 1219 | - | expression tag |
| Phe 1220 | - | expression tag |
| Gln 1221 | - | expression tag |
| Gly 1222 | - | expression tag |
| Gly 1223 | - | expression tag |
| Gly 1224 | - | expression tag |
| Gly 1225 | - | expression tag |
| Ser 1226 | - | expression tag |
| Gly 1227 | - | expression tag |
| Tyr 1228 | - | expression tag |
| Ile 1229 | - | expression tag |
| Pro 1230 | - | expression tag |
| Glu 1231 | - | expression tag |
| Ala 1232 | - | expression tag |
| Pro 1233 | - | expression tag |
| Arg 1234 | - | expression tag |
| Asp 1235 | - | expression tag |
| Gly 1236 | - | expression tag |
| Gln 1237 | - | expression tag |
| Ala 1238 | - | expression tag |
| Tyr 1239 | - | expression tag |
| Val 1240 | - | expression tag |
| Arg 1241 | - | expression tag |
| Lys 1242 | - | expression tag |
| Asp 1243 | - | expression tag |
| Gly 1244 | - | expression tag |
| Glu 1245 | - | expression tag |
| Trp 1246 | - | expression tag |
| Val 1247 | - | expression tag |
| Leu 1248 | - | expression tag |
| Leu 1249 | - | expression tag |
| Ser 1250 | - | expression tag |
| Thr 1251 | - | expression tag |
| Phe 1252 | - | expression tag |
| Leu 1253 | - | expression tag |
| Gly 1254 | - | expression tag |
| His 1255 | - | expression tag |
| His 1256 | - | expression tag |
| His 1257 | - | expression tag |
| His 1258 | - | expression tag |
| His 1259 | - | expression tag |
| His 1260 | - | expression tag |
| His 1261 | - | expression tag |
| His 1262 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 462487.5 | |
| All* | Total formula weight | 462487.5 |
