7DZD
Crystal structure of uPA in complex with cleaved camostat
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | Urokinase-type plasminogen activator | polymer | 245 | 27586.4 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (Human) | uPA |
| 2 | B (U) | 4-carbamimidamidobenzoic acid | non-polymer | 179.2 | 1 | Chemie (GBS) | |||
| 3 | C, D (U) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 4 | E (U) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
U: 16 - 242 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Cys 299 | engineered mutation |
| Gln 145 | Asn 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27586.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 479.5 | |
| All* | Total formula weight | 28065.9 |
