7DW0
SARS-CoV-2 Mpro mutant (H41A) in complex with nsp14|15 peptidyl substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3C-like proteinase | polymer | 306 | 33758.5 | 1 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Main protease,3CL-PRO,3CLp |
| 2 | B (C) | nsp14/15 peptidyl substrate | polymer | 20 | 2366.6 | 1 | UniProt (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 | |
| 3 | C, D (A, C) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A: 1 - 306 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 41 | His 3304 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36125.1 | |
| All* | Total formula weight | 36125.1 |
