7DSF

The Crystal Structure of human SPR from Biortus.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Sepiapterin reductase	polymer	278	30092.6	2	UniProt (P35270) Pfam (PF00106)	Homo sapiens (Human)	SPR
2	C, F (A, B)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	D, G (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	E, H (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	I, J (A, B)	water	water		18.0	247	Chemie (HOH)

Sequence modifications

A, B: 1 - 261 (UniProt: P35270)

PDB	External Database	Details
Met -16	-	initiating methionine
Gly -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60185.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1735.7
All*	Total formula weight	61920.9

*Water molecules are not included.