7DNQ

Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Imidazoleglycerol-phosphate dehydratase	polymer	216	23633.5	1	UniProt (P9WML9) Pfam (PF00475) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	IGPD
2	A	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	A	2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine	non-polymer		144.2	1	Chemie (HB3)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6		water	water		18.0	107	Chemie (HOH)

Sequence modifications

A: 2 - 210 (UniProt: P9WML9)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23633.5
Non-Polymers*	Number of molecules	6
	Total formula weight	387.0
All*	Total formula weight	24020.6

*Water molecules are not included.