7DNQ
Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Imidazoleglycerol-phosphate dehydratase | polymer | 216 | 23633.5 | 1 | UniProt (P9WML9) Pfam (PF00475) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | IGPD |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | F (A) | 2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine | non-polymer | 144.2 | 1 | Chemie (HB3) | |||
| 5 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | H (A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 2 - 210 (UniProt: P9WML9)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23633.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 387.0 | |
| All* | Total formula weight | 24020.6 |
