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7DL6

The co-crystal structure of DYRK2 with a small molecule inhibitor 18

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADual specificity tyrosine-phosphorylation-regulated kinase 2polymer32437675.61UniProt (Q92630)
Pfam (PF00069)
In PDB
Homo sapiens (Human)
2A[2,7-dimethoxy-9-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanolnon-polymer384.51Chemie (H96)
3waterwater18.055Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37675.6
Non-Polymers*Number of molecules1
Total formula weight384.5
All*Total formula weight38060.1
*Water molecules are not included.

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PDB entries from 2024-10-16

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