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7DJC

Crystal structure of the G26C/Q250A mutant of LeuT

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Na(+):neurotransmitter symporter (Snf family)polymer51357441.71UniProt (O67854)
Pfam (PF00209)
Aquifex aeolicusLeuT
2B
(A)
LEUCINEnon-polymer131.21Chemie (LEU)
3C, D
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
4E
(A)
octyl beta-D-glucopyranosidenon-polymer292.41Chemie (BOG)
5F
(A)
waterwater18.06Chemie (HOH)
Sequence modifications
A: 1 - 513 (UniProt: O67854)
PDBExternal DatabaseDetails
Cys 26Gly 26engineered mutation
Ala 250Gln 250engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight57441.7
Non-Polymers*Number of molecules4
Total formula weight469.5
All*Total formula weight57911.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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