7DIJ
Falcilysin in complex with MK-4815
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Falcilysin | polymer | 1158 | 135039.4 | 1 | UniProt (Q76NL8) Pfam (PF00675) Pfam (PF05193) Pfam (PF08367) Pfam (PF22516) | Plasmodium falciparum 3D7 | |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C, D, E (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | I (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | J (A) | 2-(aminomethyl)-3,5-ditert-butyl-phenol | non-polymer | 235.4 | 1 | Chemie (H8F) | |||
| 7 | K (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 8 | L (A) | water | water | 18.0 | 1017 | Chemie (HOH) |
Sequence modifications
A: 59 - 1193 (UniProt: Q76NL8)
| PDB | External Database | Details |
|---|---|---|
| Met 36 | - | initiating methionine |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
| His 40 | - | expression tag |
| His 41 | - | expression tag |
| His 42 | - | expression tag |
| Ser 43 | - | expression tag |
| Ser 44 | - | expression tag |
| Gly 45 | - | expression tag |
| Val 46 | - | expression tag |
| Asp 47 | - | expression tag |
| Leu 48 | - | expression tag |
| Gly 49 | - | expression tag |
| Thr 50 | - | expression tag |
| Glu 51 | - | expression tag |
| Asn 52 | - | expression tag |
| Leu 53 | - | expression tag |
| Tyr 54 | - | expression tag |
| Phe 55 | - | expression tag |
| Gln 56 | - | expression tag |
| Ser 57 | - | expression tag |
| Met 58 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 135039.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 834.3 | |
| All* | Total formula weight | 135873.7 |
