7DGE
intermediate state of class C GPCR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metabotropic glutamate receptor 1 | polymer | 833 | 93398.9 | 2 | UniProt (Q13255) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) | Homo sapiens (Human) | mGluR1 |
| 2 | C, D (C, D) | nanobody | polymer | 123 | 13354.7 | 2 | Lama glama | ||
| 3 | E (A) | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID | non-polymer | 189.1 | 1 | Chemie (QUS) |
Sequence modifications
A, B: 31 - 863 (UniProt: Q13255)
| PDB | External Database | Details |
|---|---|---|
| His 363 | Thr 363 | engineered mutation |
| Gln 369 | Pro 369 | engineered mutation |
| Glu 381 | Pro 381 | engineered mutation |
| Phe 383 | His 383 | engineered mutation |
| Pro 384 | Leu 384 | engineered mutation |
| Gln 385 | Leu 385 | engineered mutation |
| Ser 388 | Pro 388 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 213507.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 189.1 | |
| All* | Total formula weight | 213696.2 |
