7DFL
Cryo-EM structure of histamine H1 receptor Gq complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Histamine H1 receptor | polymer | 487 | 55856.0 | 1 | UniProt (P35367) Pfam (PF00001) | Homo sapiens (Human) | H1R,HH1R |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 339 | 37285.7 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (Human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 58 | 6375.3 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 4 | D (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 351 | 41090.6 | 1 | Pfam (PF00503) UniProt (by SIFTS) (P63096) UniProt (by SIFTS) (P50148) | Homo sapiens | |
| 5 | E (C) | scFv16 | polymer | 251 | 26679.7 | 1 | Homo sapiens | ||
| 6 | F (R) | HISTAMINE | non-polymer | 111.1 | 1 | Chemie (HSM) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 167287.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 111.1 | |
| All* | Total formula weight | 167398.6 |
