7DD7

Structure of Calcium-Sensing Receptor in complex with Evocalcet

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Calcium-Sensing Receptor	polymer	1069	119314.2	2	UniProt (by SIFTS) (A0A8I3AZV5)	Gallus gallus (Chicken)
2	C, D, E, F (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3	G, P (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL) PubChem (312)
4	H, I, O, Q, R... (A, B)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA) PubChem (271)
5	J, K, L, T, U... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
6	M, W (A, B)	TRYPTOPHAN	non-polymer		204.2	2	Chemie (TRP)
7	N, X (A, B)	2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid	non-polymer		374.5	2	Chemie (H43) PubChem (71242808) PubChem (78045318) PubChem (135356263) PubChem (154027863) PubChem (175666207) PubChem (175666265) PubChem (175666302)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	238628.5
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	18
	Total formula weight	2796.0
All*	Total formula weight	243122.1

*Water molecules are not included.