7DCS

Crystal structure of HSF1 DNA-binding domain in complex with 3-site HSE DNA (23 bp)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Heat shock factor protein 1	polymer	113	13214.0	6	UniProt (Q00613) Pfam (PF00447) In PDB	Homo sapiens (Human)	HSF 1,Heat shock transcription factor 1,HSTF 1
2	G, I	DNA (5'-D(*TP*GP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*GP*A)-3')	polymer	23	7111.6	2		Homo sapiens
3	H, J	DNA (5'-D(*AP*TP*CP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*CP*C)-3')	polymer	23	7009.5	2		Homo sapiens
4	A, B, C, D, F	SODIUM ION	non-polymer		23.0	5	Chemie (NA)
5		water	water		18.0	391	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 15 - 120 (UniProt: Q00613)

PDB	External Database	Details
Gly 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	107526.4
Non-Polymers*	Number of molecules	5
	Total formula weight	114.9
All*	Total formula weight	107641.4

*Water molecules are not included.