7DCJ

Crystal structure of HSF1 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Heat shock factor protein 1	polymer	113	13214.0	2	UniProt (Q00613) Pfam (PF00447) In PDB	Homo sapiens (Human)	HSF 1,Heat shock transcription factor 1,HSTF 1
2	C, D	DNA (5'-D(*GP*CP*CP*GP*AP*AP*TP*AP*TP*TP*CP*GP*G)-3')	polymer	14	4280.8	2		Homo sapiens
3	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4		water	water		18.0	307	Chemie (HOH)

Sequence modifications

A, B: 15 - 120 (UniProt: Q00613)

PDB	External Database	Details
Gly 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	34989.6
Non-Polymers*	Number of molecules	2
	Total formula weight	46.0
All*	Total formula weight	35035.6

*Water molecules are not included.