7DB6
human melatonin receptor MT1 - Gi1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 344 | 37799.3 | 1 | Pfam (PF00400) UniProt (by SIFTS) (P62873) In PDB | Rattus rattus | |
| 3 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 68 | 7547.7 | 1 | UniProt (P63212) Pfam (PF00631) In PDB | Bos taurus (Bovine) | G gamma-I |
| 4 | E | scFv16 | polymer | 260 | 27720.8 | 1 | Mus musculus | ||
| 5 | D | Melatonin receptor type 1A | polymer | 372 | 42222.8 | 1 | UniProt (P48039) Pfam (PF00001) In PDB | Homo sapiens (Human) | Mel1a receptor |
| 6 | D | N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide | non-polymer | 259.3 | 1 | Chemie (JEV) |
Sequence modifications
C: 1 - 67 (UniProt: P63212)
D: 1 - 340 (UniProt: P48039)
| PDB | External Database | Details |
|---|---|---|
| Ser 68 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -25 | - | initiating methionine |
| Lys -24 | - | expression tag |
| Thr -23 | - | expression tag |
| Ile -22 | - | expression tag |
| Ile -21 | - | expression tag |
| Ala -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Tyr -17 | - | expression tag |
| Ile -16 | - | expression tag |
| Phe -15 | - | expression tag |
| Cys -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Val -12 | - | expression tag |
| Phe -11 | - | expression tag |
| Ala -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Tyr -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Glu 341 | - | expression tag |
| Asn 342 | - | expression tag |
| Leu 343 | - | expression tag |
| Tyr 344 | - | expression tag |
| Phe 345 | - | expression tag |
| Gln 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 155705.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 259.3 | |
| All* | Total formula weight | 155964.9 |
