7DAA
Crystal structure of basigin complexed with anti-basigin Fab fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Isoform 2 of Basigin | polymer | 176 | 19592.8 | 1 | UniProt (P35613) Pfam (PF13927) In PDB | Homo sapiens (Human) | 5F7,Collagenase stimulatory factor,Extracellular matrix metalloproteinase inducer,EMMPRIN,Hepatoma-associated antigen,HAb18G,Leukocyte activation antigen M6,OK blood group antigen,Tumor cell-derived collagenase stimulatory factor,TCSF |
| 2 | L | Light chain of antibody Fab fragment | polymer | 218 | 23319.9 | 1 | Homo sapiens (Human) | ||
| 3 | H | Heavy chain of antibody Fab fragment | polymer | 217 | 22786.5 | 1 | Homo sapiens (Human) | ||
| 4 | A, L, H | CADMIUM ION | non-polymer | 112.4 | 16 | Chemie (CD) |
Sequence modifications
A: 103 - 269 (UniProt: P35613)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | - | expression tag |
| Gln 152 | Asn 152 | engineered mutation |
| Gln 186 | Asn 186 | engineered mutation |
| Asp 270 | - | expression tag |
| Tyr 271 | - | expression tag |
| Lys 272 | - | expression tag |
| Asp 273 | - | expression tag |
| Asp 274 | - | expression tag |
| Asp 275 | - | expression tag |
| Asp 276 | - | expression tag |
| Lys 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65699.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1798.6 | |
| All* | Total formula weight | 67497.8 |
